Research

Research Overview

My research aims to understand how genetic alterations reshape cellular behavior and contribute to disease.

I am particularly interested in using rare genetic diseases and tumor-associated mutations as biological models to uncover fundamental mechanisms of human biology.

Current Research Areas

NF2 and Tumor Biology

I study how loss of NF2 alters cellular signaling, tissue homeostasis, and tumor development.

This work focuses on identifying molecular changes that may explain the growth and progression of NF2-associated tumors.

Cellular Signaling

I am interested in how signaling networks control cell growth, survival, metabolism, and differentiation.

My current work examines pathways involved in tumor biology and disease-associated cellular dysfunction.

Cholesterol Metabolism

Abnormal cholesterol regulation can influence membrane organization, signaling, and cell growth.

I investigate how altered cholesterol metabolism may contribute to disease phenotypes and tumor progression.

Rare Genetic Disease

Rare genetic diseases provide precise biological models in which a specific genetic change can reveal the function of a gene, pathway, or cellular process.

I use these diseases as a framework for understanding broader principles of human biology.

Experimental Approaches

My research uses a combination of:

• Cell culture models
• Molecular and biochemical assays
• Western blotting
• Fluorescence imaging
• Cell viability and proliferation assays
• Animal disease models
• Genetic manipulation
• Functional analysis of signaling pathways

Long-Term Direction

My long-term goal is to connect genetic variation with molecular mechanisms, cellular phenotypes, and disease development.

Through this approach, I hope to build a deeper and more integrated understanding of human biology.